Detailed Description

Jiyonort-N is a combination medicine used for the treatment of neuropathic pain. This medicine decreases the pain by stopping the movement of pain signals to the brain.

Jiyonort-N is taken by mouth, with or without food, preferably at night. It is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. In case you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly without talking to the doctor as it may worsen your symptoms.

Some common side effects of this medicine include constipation, difficulty in urination, weight gain, tiredness, and dryness in the mouth. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain, and to control it, you should exercise regularly and take a balanced diet. Remember to inform the doctor if you develop any unusual changes in mood, as this medicine may lead to suicidal thoughts.

Before taking this medicine, let your doctor know if you suffer from kidney or liver disease. Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Uses

• Used in treatment of Neuropathic Pain

Benefits

• Jiyonort-N is a combination medicine used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles, or spinal cord injury. It reduces pain and its associated symptoms, such as mood changes, sleep problems, and tiredness. It is thought to work by interfering with pain signals that travel through the damaged nerves to the brain.
• By choosing Jiyyo’s generic version, you receive the exact therapeutic benefit of the leading brand at a fraction of the cost, backed by our quality guarantee.

Side Effects

• Sleepiness

• Tiredness

• Orthostatic hypotension (sudden lowering of blood pressure on standing)

• Increased heart rate

• Uncoordinated body movements

• Constipation

• Difficulty in urination

• Weight gain

• Dizziness

• Blurred vision

• Decreased white blood cell count

• Peripheral edema

• Weakness

• Dryness in mouth

• Impotence

• Indigestion

• Insomnia (difficulty in sleeping)

• While Jiyyo’s doctors trust this product, please consult a healthcare professional before use. Jiyyo is committed to your safety and transparency.

How to use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Jiyonort-N Tablet may be taken with or without food.

Consult with a Jiyyo partner doctor for a personalized dosage plan tailored to your health needs.

How drug works

Jiyonort-N is a combination of two medicines: Gabapentin and Nortriptyline. Gabapentin is an alpha-2-delta ligand that decreases pain by modulating calcium channel activity in nerve cells. Nortriptyline is a tricyclic antidepressant that increases the levels of chemical messengers (serotonin and noradrenaline) which help block the transmission of pain signals in the brain. Together, they relieve neuropathic pain (pain caused by damaged nerves).

Our formulation ensures optimal bioavailability, meaning the body absorbs the active ingredients efficiently to provide faster relief.

Safety advice

• Alcohol – Alcohol should be used with caution while taking Jiyonort-N.

  Pregnancy –Information regarding the use of Jiyonort-N during pregnancy is not available. Please consult your doctor.

  Breastfeeding –Jiyonort-N may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into breast milk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

  Driving –Jiyonort-N may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

  Kidney – Jiyonort-N should be used with caution in patients with kidney disease. Dose adjustment may be needed.

  Liver – Jiyonort-N should be used with caution in patients with liver disease. Dose adjustment may be needed. Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine. Use of Jiyonort-N is not recommended in patients with severe liver disease.

Storage Instructions

FAQs

Q. What is Jiyonort-N?

Jiyonort-N is a combination of two medicines: Gabapentin and Nortriptyline. This medicine is useful in the treatment of nerve pain (neuropathic pain). It calms damaged or overactive nerves by acting on the brain, thereby decreasing the pain sensation.

Q. Can I stop taking Jiyonort-N when my pain is relieved?

No, you should not stop taking Jiyonort-N even if your pain is relieved. Continue to take it as advised by your doctor. Suddenly stopping Jiyonort-N may cause withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain, and sweating. You may need to gradually taper the dose before stopping the medication completely.

Q. How to manage weight gain associated with the use of Jiyonort-N?

Jiyonort-N can increase appetite, which may lead to weight gain. To prevent this:

Eat a healthy, balanced diet without increasing portion sizes.

Avoid high-calorie foods such as soft drinks, oily foods, chips, cakes, biscuits, and sweets.

For between-meal hunger, choose fruits, vegetables, and low-calorie snacks.

Regular exercise will help prevent weight gain.

Q. Can Jiyonort-N affect my sexual life?

Yes, Jiyonort-N may affect sexual life in both men and women. Common issues include decreased sexual desire, erectile dysfunction, and difficulty reaching orgasm. It may also reduce satisfaction and cause discomfort during intercourse. Discuss any such problems with your doctor, but do not stop taking the medicine on your own.

Q. Are there any serious side effects associated with Jiyonort-N?

Serious side effects are uncommon but may occur. Contact your doctor immediately if you notice:

Changes in body temperature

Difficulty breathing

Rapid heartbeat (palpitations)

Weakness, unsteadiness, or poor coordination

Unusual changes in mood or behavior, restlessness, or nervousness

Signs of depression or hallucinations

Blurred or double vision, involuntary eye movements

Frequent infections (fever, severe chills, sore throat, mouth ulcers)

Q. How long will Jiyonort-N take to act?

Initial benefits may be seen after 2 weeks of treatment. Full effects may take 2–3 months or longer in some patients.

Q. What if I forget to take Jiyonort-N?

If it is almost time for your next dose, skip the missed dose and take the next dose at the scheduled time. Otherwise, take it as soon as you remember and continue your regular schedule. Do not double the dose to make up for a missed one. If unsure, ask your doctor.

Q. What if I take too much of this drug by mistake?

Contact your doctor immediately or seek emergency help, even if you feel fine. Overdose may cause drowsiness, weakness, unsteadiness, double vision, slurred speech, diarrhea, confusion, dizziness, body temperature changes, difficulty breathing, or increased heartbeat.

Q. Is there anything I need to avoid while taking Jiyonort-N?

Avoid alcohol, as it can increase drowsiness and other side effects.

Be cautious while driving, operating machinery, or performing activities requiring alertness.

Grapefruit and grapefruit juice may interact with this medicine.

Avoid excessive sunlight exposure; use sunscreen and protective clothing outdoors.

Q. How often should I see the doctor?

Regular follow-ups may be needed. Consult your doctor if your symptoms persist, if the recommended dose does not provide relief, or if you experience unwanted side effects affecting your daily activities.

Q. Can Jiyonort-N cause sleepiness or drowsiness?

Yes, Jiyonort-N may cause drowsiness or sudden sleep episodes. Avoid driving, operating machinery, or other potentially dangerous activities until you know how it affects you. Inform your doctor if such episodes occur.

Q. Will Jiyonort-N be more effective if taken in higher doses?

No, higher than recommended doses do not improve effectiveness and may increase the risk of serious side effects or toxicity. Consult your doctor if symptoms are not relieved by the recommended dose.

Q. What are the storage conditions for Jiyonort-N?

Keep tablets in their original pack until use.

Store in a cool, dry place.

Keep out of reach of children.

Dispose of unused medication safely to prevent accidental ingestion.

Disclaimer

• Jiyyo ‘s sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should not be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor through Jiyyo’s platform and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship. For any discussion, clarification, or health-related queries, please consult Jiyyo’s qualified doctors.