Detailed Description

Apzoller-DSR is a prescription medicine used to treat gastroesophageal reflux disease (Acid reflux), dyspepsia (indigestion), and gastritis. It helps treat the conditions by reducing the amount of acid in the stomach thereby relieving symptoms of acidity such as heartburn, stomach pain, or irritation. Apzoller-DSR also neutralizes the acid in the stomach and promotes easy passage of gas to reduce stomach discomfort. It is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking Apzoller-DSR for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.               At Jiyyo, we bridge the gap between quality and affordability. Apzoller-DSR is manufactured in state-of-the-art facilities following strict global safety standards. Because of our commitment to excellence, Jiyyo's own network of doctors frequently prescribes this medicine, ensuring patients receive reliable treatment they can trust.

Uses

• • Gastroesophageal Reflux Disease (GERD) / Acid Reflux: Relieves symptoms like heartburn, chest burning, and the backflow of stomach acid into the food pipe (esophagus).
  • Indigestion and Bloating: Improves digestion, reduces feelings of fullness after meals, belching, and general discomfort.
  • Gastric and Duodenal Ulcers: Lowers stomach acid levels to help heal existing ulcers and prevent their recurrence.

• Gastritis: Reduces inflammation, pain, and burning sensations in the stomach lining.

• Nausea and Vomiting: Domperidone helps control these symptoms by blocking signals in the brain and increasing stomach movement.

• Erosive Esophagitis: Promotes healing of the inflamed or damaged lining of the food pipe caused by repeated acid exposure. 

Benefits

Apzoller-DSR provides dual benefits by reducing stomach acid production and improving the movement of the digestive tract. This makes it effective for treating a range of gastrointestinal disorders.

By choosing Jiyyo’s generic version, you receive the exact therapeutic benefit of the leading brand at a fraction of the cost, backed by our quality guarantee.

 

 

Side Effects

• Diarrhea
• Flatulence
• Dizziness
• Headache
• Nausea
• Vomiting,
• Abdominal pain
• Joint pain
• While Jiyyo’s doctors trust this product, please consult a healthcare professional before use. Jiyyo is committed to your safety and transparency.

How to use

How drug works

• Pantoprazole (Proton Pump Inhibitor – PPI): Pantoprazole works by reducing the amount of acid produced in the stomach. It achieves this by irreversibly blocking an enzyme system in the stomach lining called the proton pump (H+/K+ ATPase) which is the final step in acid production. This lowers the overall acidity in the stomach, which helps to relieve heartburn and allows damaged tissues in the esophagus and stomach to heal.
• Domperidone (Prokinetic and Antiemetic): Domperidone increases the movements or contractions of the stomach and intestines, acting on the upper digestive tract. This action, known as a prokinetic effect, helps food move more quickly through the digestive system, reducing feelings of bloating, fullness, and indigestion. Domperidone also acts as an antiemetic (anti-vomiting agent) by blocking dopamine receptors in the brain’s “vomiting center” (chemoreceptor trigger zone), thereby preventing nausea and vomiting. 
• The Jiyyo Difference: “Our formulation ensures optimal bioavailability, meaning the body absorbs the active ingredients efficiently to provide faster relief.”

Safety advice

• Heart Issues: Domperidone is associated with serious cardiac adverse events, including irregular heartbeat (arrhythmias), QT prolongation, cardiac arrest, and sudden death. The risk is higher in patients over 60 years old or those taking daily doses greater than 30 mg, or individuals with pre-existing heart conditions or electrolyte imbalances (low magnesium or potassium).
• Liver Disease: Use with caution in patients with kidney or liver disease; it is generally contraindicated in moderate to severe liver impairment.
• Gastrointestinal Issues: Do not use if you have a history of gastrointestinal bleeding, mechanical obstruction, or perforation, as stimulating gastric motility could be harmful.
• Drug Interactions: This combination can interact with many other medicines, including certain antifungals (e.g., ketoconazole), anti-HIV drugs (e.g., atazanavir), some antibiotics (e.g., erythromycin), heart medicines (e.g., digoxin), and blood thinners (e.g., warfarin).
• Allergies: Do not take if you have a known hypersensitivity to pantoprazole, domperidone, or any related medicines. 

• Bone Fractures: Especially of the hip, wrist, or spine.
• Nutrient Deficiencies: Such as low magnesium (hypomagnesemia) and vitamin B12 deficiency.
• Infections: Increased susceptibility to certain gut infections, including Clostridioides difficile-associated diarrhea. 

• Pregnancy and Breastfeeding: Not generally recommended unless the doctor determines the benefits outweigh the risks. Domperidone passes into breast milk and could pose risks to the infant.
• Driving: The medicine may cause dizziness or visual disturbances; avoid driving or operating machinery if affected.
• Lifestyle: Avoid alcohol and smoking, as they can worsen acid reflux symptoms and reduce the medicine’s effectiveness. Grapefruit and cranberry juice should also be avoided due to potential interactions. 

Storage Instructions

Store Apzoller in a cool, dry place, protected from moisture, heat, and direct light, usually at room temperature (below 25°C/77°F). Keep it in its original tightly closed container, away from children.

FAQs

Disclaimer

• Jiyyo ‘s sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should not be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor through Jiyyo’s platform and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship. For any discussion, clarification, or health-related queries, please consult Jiyyo’s qualified doctors.